Antoinette I.M. van Laarhoven:


Psychophysics of itch and pain



Welcome!


About Me PhD Students and Research Assistants CV Publications Contact

About Dr. van Laarhoven


At Leiden University, the Netherlands, Antoinette van Laarhoven, PhD investigates the role of psychophysical and psychoneurophysiological processes in itch and pain, for instance due to inflammatory (e.g., atopic dermatitis, rheumatoid arthritis) and non-inflammatory (e.g., post-burn itch, fibromyalgia) conditions. Her research line is aimed at elucidating symptom perception, with a particular focus on how attention and expectancy play a role in aggravating and reducing itch and pain.


She applies various measures within her experimental research, including itch and pain inductions by quantitative sensory testing (QST), electroencephalography (EEG), behavioral tasks (e.g., the dot-probe task, Flanker task), and eye tracking. Recently, she implemented the use of virtual reality in her research.

 

The knowledge obtained may contribute to prevention, early diagnosis of patients at risk to develop chronic itch or pain (e.g., based on biomarkers), and more effective treatment of chronic diseases. Her overall target is to improve patients' wellbeing.

PhD students and research assistants

Current PhD students (as daily supervisor)

Jennifer M. Becker

Attentional processing of itch:

A psychophysical approach

LingLing Weng

Transferability of the placebo and nocebo effect between itch and pain

Gita P. Nadinda

Expect to avoid: The role of expectancy and avoidance in the chronification of somatic symptoms

Former PhD students (as daily supervisor)

Danielle J. P. Bartels

Placebo and nocebo effects on itch:

An experimental approach (finished 2020)

Research assistants

Current Assistants

Jeltje Broekhof


Former Assistants

Linda Schur

Shir van den Ende

Sophia Bremo

Isabella Saccardi

Michiel van den Nouwenland

Anne Nijboer

Samantha Millard

Sarah Vreijling

Gudrun Eisele

Mathilde Pronk

Rik Schalbroeck

Charlotte Piechaczek


CV

2014 – present 

Assistant professor at Health, Medical and Neuropsychology Unit, Leiden University, Leiden, the Netherlands.

- Oct - Dec 2016: Stay at the Center for Sensory-Motor Interaction (SMI), Aalborg University, Denmark for research on sensitization processes, including conducting an experimental study on conditioned itch and pain modulation and writing a meta-analysis. Hosted by Prof. L. Arendt-Nielsen and Dr. H.H. Andersen.

- Nov 2014: Short stay at the Centre for pain research, University of Bath, UK on the role of attention in itch and pain. Hosted by Prof. C. Eccleston, Prof. E. Keogh, and Dr. N. Attridge.


2011 – 2013 

Post-doctoral researcher at Department of Medical Psychology, Radboudumc, Nijmegen, the Netherlands.


2006 - 2011 

PhD candidate. PhD degree in Medical Science obtained 30 March ‘12 for the PhD thesis entitled Itch and pain: Common and distinct psycho-physiological factors. Department of Medical Psychology, Radboudumc, Nijmegen, the Netherlands.


2004 – 2006 

Bachelor and Master Biomedical Sciences (MSc), Radboud University, Nijmegen, the Netherlands. 

Research internships: Department of Dermatology (9 months) and Department of Medical Psychology (6 months), Radboudumc, Nijmegen, the Netherlands; Department of Biochemistry (5 months), Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.

Bachelor

  • Coordinator and lecturer of the course Pharmacological and biological approaches to clinical and health psychology - 3rd year bachelor’s Psychology elective.

https://studiegids.universiteitleiden.nl/en/courses/111066/pharmacological-and-biological-approaches-to-clinical-and-health-psychology


  • Workgroup teacher of the course Health and Medical Psychology - 3rd year bachelor’s Psychology specialisation course.

https://studiegids.universiteitleiden.nl/en/courses/111056/health-and-medical-psychology


  • Supervisor of Bachelor projects Psychology - 3rd year bachelor’s Psychology (>40 thesis students supervised).

https://studiegids.universiteitleiden.nl/en/courses/111463/bachelor-project-psychology



Master

  • Coordinator and work group teacher of the course Psychological Assessment and Interventions in Chronic Disease - Health and Medical specialisation Master Psychology.

https://studiegids.universiteitleiden.nl/en/courses/114628/psychological-assessment-and-interventions-in-chronic-disease


  • Coordinator and lecturer of the course Research Topics in Health Promotion – Research Master Psychology. 

https://studiegids.universiteitleiden.nl/en/courses/114585/research-topics-in-health-promotion


  • Thesis supervisor (research) master students (of >25 thesis students supervised).  

https://studiegids.universiteitleiden.nl/en/courses/114610/master-thesis-in-msc-psychology


2019 

Netherlands Organization for Scientifc Research (NWO) Gravitation Grant for the project: “New Science of Mental Disorders”. Consortium led by Prof. A. Jansen. (€19.700.000) 

Role: Young Talent (described as having the potential to become an international leader in the field). Antoinette van Laarhoven is part of the Mind-Body Interface team within this project. 


2018 

Research project grant from Leiden University Profile area Brain function and dysfunction over the lifespan: “Full body mimicry using virtual reality” (€ 60.900). 

Role: Project leader and Co-PI. 


2017  

Research project grant from the Leiden University Fund - Den Dulk-Moermans Fund for scientific research in the field of health in a broad sense “Unconscious attentional processing of itch: towards an innovative training” (€ 24.968). 

Role: PI


2015  

NWO Talent Programme:  personal Veni grant for the project: “Itch even harder to ignore than pain? A psychophysiological approach to attentional processing of somatosensory sensations.” (€250.000). 

Role: PI


2014  

Research project grant from the Dutch Burns Foundation for the project: “Psychoneurobiology of itch symptoms in patients following burn injuries.” (€40.000). 

Role: Project leader and Co-PI.

  • 2019 John de Korte Travel Grant for the 18th Congress of the European Society for Dermatology and Psychiatry (ESDaP) Giessen, Germany, 20-22 June 2019.
  • 2015 International Forum for the Study of itch (IFSI) Travel grant for the 8th World Congress on Itch, 2015, Nara, Japan. 
  • 2013 International Forum for the Study of itch (IFSI) Travel grant for the 7th World Congress on Itch, 2013, Boston, USA. 
  • 2013 Association for Researchers in Psychology & Health (ARPH) PhD thesis award for the best PhD thesis on psychology and health in 2012. 
  • 2012 Herman Musaph literature award for Psychodermatology of the Herman Musaph Stichting for the best publication in the field of psychodermatology in 2010-2011. 

Conference and symposium organization


2021 NVPD (Dutch Society for Psychodermatology) symposium about psycho-dermato-oncology: Skin cancer, why me? Amsterdam, the Netherlands (online due to the COVID-19 pandemic).


2020 Member of local arrangements committee (LAC) of the IASP 2020 World Congress on Pain. Amsterdam, the Netherlands. Unfortunately, the conference had eventually to be cancelled due to the COVID-19 pandemic. 


2019 NVPD symposium: Itch! What to do now? Amsterdam, the Netherlands.


2018 NVPD symposium: Stress under the skin. Amsterdam, the Netherlands. 


2017 Chair of symposium: Psychological factors influencing pain perception: an experimental approach at Sixth conference of the Association for Researchers in Psychology and Health (ARPH), Leiden, the Netherlands. 


2016 NVPD/AMC symposium: Psychodermatology: state of the art and future directions. Amsterdam, the Netherlands.


2015 NVPD symposium: Psychodermatology: focus on the child. Amsterdam, the Netherlands.


Committee and board tasks

Local

2019- present 

Freezer coordinator of Faculty of Social Sciences, Leiden University, Leiden, the Netherlands.


2019- present

Lab-researchers’ delegate in Institutional Beta Research Committee (IBBC), Institute of Psychology, Leiden University, Leiden.


2015 – 2020 

Initiator and coordinator of OLI (research lunch intervision) Research Discussion Meetings within the Health, Medical, and Neuropsychology unit, Leiden University, Leiden.


2014 - present 

Lab coordinator beta labs Health, Medical, and Neuropsychology unit, Leiden University, Leiden.


2008 – 2010 

Board member PhD Council Nijmegen Centre for Evidence Based Practice (NCEBP), secretary 2009-2010, Radboudumc, Nijmegen, the Netherlands.



National / Binational (the Netherlands & Belgium)


2014 – present 

Board member of the Dutch Society for Psychodermatology (NVPD), Secretary since 2019.


2014/2015/2019

Committee member of the Poster award at the annual ARPH Conferences.


2018 

Committee member of Best PhD thesis award of the Association for Researchers in Psychology and Health (ARPH).


2015

Committee member of Annual Article Contest 2015 of the binational Postgraduate School Experimental Psychopathology (EPP).



International

2020 – present 

Committee member of International Forum for the Study of Itch (IFSI) Special Interest Group (SIG) on Psychological factors and itch.


2015 – present 

Committee member of IFSI SIG  on Itch Questionnaires.



Membership of national and international committees and institutes

  • Member of the Leiden Institute for Brain and Cognition (LIBC)
  • Senior member of the Postgraduate School Experimental Psychopathology (EPP)
  • Member of Association for Researchers in Psychology and Health (ARPH)
  • Member of the International Association for the Study of Pain (IASP)
  • Member of the International Forum for the Study on Itch (IFSI)

PUBLICATIONS (per topic)

A full list of publications can be found here

PDF Publications in chronological order

Publications on attention in chronological order


  • Nadinda, P. G., Van Laarhoven, A. I. M., Evers, A., Maas, J., & Van Beugen, S. (2023). Itch-Related avoidance and attentional biases in patients with psoriasis? Journal of Investigative Dermatology. https://doi.org/10.1016/j.jid.2023.02.032
  • Becker, J. M., Holle, H., van Ryckeghem, D. M. L., Van Damme, S., Crombez, G., Veldhuijzen, D. S., Evers, A. W. M., Rippe, R. C. A. & van Laarhoven, A. I. M. (2022). No preconscious attentional bias towards itch in healthy individuals. PLOS ONE, 17(9), e0273581. https://doi.org/10.1371/journal.pone.0273581
  • Etty, S., George, D. N., Van Laarhoven, A. I., & Holle, H. (2022). Acute Itch Induces Attentional Avoidance of Itch-related Information. Acta Dermato-Venereologica, 102, adv00691. https://doi.org/10.2340/actadv.v102.1626
  • Van Laarhoven, A. I. M., Becker, J. M., Van Ryckeghem, D. M. L., Van Damme, S., Crombez, G., & Wiers, R. W. H. J. (2021). Attentional Bias Modification Training for Itch: A Proof-of-Principle Study in Healthy Individuals. Frontiers in Medicine, 8, 627593. https://doi.org/10.3389/fmed.2021.627593
  • Becker, J. M.,* Vreijling, S. R.,* Dobbinga, S., Giesbers, J. J. J., Evers, A. W. M., Veldhuijzen, D. S., & van Laarhoven, A. I. M. (2020). Attentional Bias Towards Visual Itch and Pain Stimuli in Itch- and Pain-free Individuals? Acta Dermato Venereologica, 100(14), adv00199. https://doi.org/10.2340/00015555-3537
  • Van Laarhoven, A. I. M., & Holle, H. (2019). Optimizing audiovisual itch induction: the role of attention and expectancy. British Journal of Dermatology, 182(5), 1088–1089. https://doi.org/10.1111/bjd.18596
  • Van Laarhoven, A. I. M., Van Damme, S., Lavrijsen, A. P. M., Van Ryckeghem, D. M., Crombez, G., & Evers, A. W. M. (2017). Do Tonic Itch and Pain Stimuli Draw Attention towards Their Location? BioMed Research International, 2031627. https://doi.org/10.1155/2017/2031627
  • Van Laarhoven, A. I. M., Van Damme, S., Lavrijsen, A. P. M., Van Ryckeghem, D. M., Crombez, G., & Evers, A. W. M. (2017). Attentional processing of itch. Psychological Research, 82(5), 876–888. https://doi.org/10.1007/s00426-017-0878-2
  • Van Laarhoven, A. I. M., Kraaimaat, F. W., Wilder-Smith, O. H., & Evers, A. W. M. (2010). Role of Attentional Focus on Bodily Sensations in Sensitivity to Itch and Pain. Acta Dermato Venereologica, 90(1), 46–51. https://doi.org/10.2340/00015555-0743

* joint first authorship


Publications on expectancy in chronological order


  • Thomaidou, M. A., Blythe, J. S., Peerdeman, K. J., Van Laarhoven, A. I. M., Van Schothorst, M. M. E., Veldhuijzen, D. S., & Evers, A. (2023). Learned nocebo effects on cutaneous sensations of pain and itch: A systematic review and meta-analysis of experimental behavioral studies on healthy humans. Psychosomatic Medicine, 85(4), 308–321. https://doi.org/10.1097/psy.0000000000001194
  • Blythe, J. S., Thomaidou, M. A., Peerdeman, K. J., Van Laarhoven, A. I. M., Van Schothorst, M. M. E., Veldhuijzen, D. S., & Evers, A. W. M. (2022). Placebo effects on cutaneous pain and itch: A systematic review and meta-analysis of experimental results and methodology. Pain, 164(6), 1181–1199. https://doi.org/10.1097/j.pain.0000000000002820
  • Meeuwis, S. H., Skvortsova, A., van Laarhoven, A. I. M., Holle, H. & Evers, A. W. M. (2022). Can contagious itch be affected by positive and negative suggestions? Experimental Dermatology, 31(12), 1853–1862. https://doi.org/10.1111/exd.14663
  • Weng, L., van Laarhoven, A. I. M., Peerdeman, K. J. & Evers, A. W. M. (2022). Do individual psychological characteristics predict induction and generalization of nocebo and placebo effects on pain and itch? Frontiers in Psychiatry, 13; 838578. https://doi.org/10.3389/fpsyt.2022.838578
  • Weng, L., Laarhoven, A. I. M., Peerdeman, K. J., & Evers, A. W. M. (2022). Induction and generalization of nocebo effects on itch. Experimental Dermatology, 31(6), 878–889. https://doi.org/10.1111/exd.14522
  • Blythe, J. S., Peerdeman, K. J., Veldhuijzen, D. S., Schothorst, M. M. E., Thomaïdou, M. A., Van Laarhoven, A. I. M., & Evers, A. W. M. (2021). Nocebo Effects on Cowhage-evoked Itch: A Randomized Controlled Trial of Classical Conditioning and Observational Learning. Acta Dermato Venereologica, 101(1), adv00370. https://doi.org/10.2340/00015555-3723
  • Thomaidou, M. A.,* Blythe, J. S.,* Houtman, S. J.,* Veldhuijzen, D. S., Van Laarhoven, A. I. M., & Evers, A. W. M. (2021). Temporal structure of brain oscillations predicts learned nocebo responses to pain. Scientific Reports, 11, 9807. https://doi.org/10.1038/s41598-021-89368-0
  • Weng, L., Peerdeman, K. J., Della Porta, D., Van Laarhoven, A. I., & Evers, A. W. (2021). Can placebo and nocebo effects generalize within pain modalities and across somatosensory sensations? Pain, 163(3), 548–559. https://doi.org/10.1097/j.pain.0000000000002390
  • Meeuwis, S. H., Van Middendorp, H., Van Laarhoven, A. I. M., Van Leijenhorst, C., Pacheco-Lopez, G., Lavrijsen, A. P. M., Veldhuijzen, D. S., & Evers, A. W. M. (2020). Placebo and nocebo effects for itch and itch-related immune outcomes: A systematic review of animal and human studies. Neuroscience & Biobehavioral Reviews, 113, 325–337. https://doi.org/10.1016/j.neubiorev.2020.03.025
  • Review: Blythe, J. S., Peerdeman, K. J., Veldhuijzen, D. S., Van Laarhoven, A. I. M., & Evers, A. W. M. (2019). Placebo and nocebo effects on itch: a review of experimental methods. Itch, 4(3), e27. https://doi.org/10.1097/itx.0000000000000027
  • Meeuwis, S. H., Van Middendorp, H., Van Laarhoven, A. I. M., Veldhuijzen, D. S., Lavrijsen, A. P. M., & Evers, A. W. M. (2019). Effects of Open- and Closed-Label Nocebo and Placebo Suggestions on Itch and Itch Expectations. Frontiers in Psychiatry, 10, 436. https://doi.org/10.3389/fpsyt.2019.00436
  • Van Laarhoven, A. I. M., & Holle, H. (2019). Optimizing audiovisual itch induction: the role of attention and expectancy. British Journal of Dermatology, 182(5), 1088–1089. https://doi.org/10.1111/bjd.18596
  • Bartels, D. J. P., Van Laarhoven, A. I. M., Donders, A. R. T., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2018). Nocebo Effects and Scratching Behaviour on Itch. Acta Dermato Venereologica, 98(10), 943–950. https://doi.org/10.2340/00015555-2979
  • Bartels, D. J. P., Van Laarhoven, A. I. M., Heijmans, N., Hermans, D., Debeer, E., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2017). Cognitive Schemas in Placebo and Nocebo Responding: Role of Autobiographical Memories and Expectations. Clinical Therapeutics, 39(3), 502–512. https://doi.org/10.1016/j.clinthera.2017.02.004
  • Bartels, D. J. P., Van Laarhoven, A. I. M., Stroo, M., Hijne, K., Peerdeman, K. J., Donders, A. R. T., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2017). Minimizing nocebo effects by conditioning with verbal suggestion: A randomized clinical trial in healthy humans. PLOS ONE, 12(9), e0182959. https://doi.org/10.1371/journal.pone.0182959
  • Peerdeman, K. J., Tekampe, J., Van Laarhoven, A. I. M., Van Middendorp, H., Rippe, R. C. A., Peters, M. L., & Evers, A. W. M. (2017). Expectations about the effectiveness of pain- and itch-relieving medication administered via different routes. European Journal of Pain, 22(4), 774–783. https://doi.org/10.1002/ejp.1163
  • Peerdeman, K. J., Van Laarhoven, A. I. M., Bartels, D. J. P., Peters, M. L., & Evers, A. W. M. (2017). Placebo-like analgesia via response imagery. European Journal of Pain, 21(8), 1366–1377. https://doi.org/10.1002/ejp.1035
  • Review: Peerdeman, K. J., Van Laarhoven, A. I. M., Keij, S. M., Vase, L., Rovers, M. M., Peters, M. L., & Evers, A. W. M. (2016). Relieving patients’ pain with expectation interventions. Pain, 157(6), 1179–1191. https://doi.org/10.1097/j.pain.0000000000000540
  • Review: Peerdeman, K. J., Van Laarhoven, A. I. M., Peters, M. L., & Evers, A. W. M. (2016). An Integrative Review of the Influence of Expectancies on Pain. Frontiers in Psychology, 7, 1270. https://doi.org/10.3389/fpsyg.2016.01270
  • Review: Bartels, D. J. P., Van Laarhoven, A. I. M., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2015). Placebo and nocebo effects on itch: effects, mechanisms, and predictors. European Journal of Pain, 20(1), 8–13. https://doi.org/10.1002/ejp.750
  • Peerdeman, K. J., Van Laarhoven, A. I. M., Donders, A. R. T., Hopman, M. T., Peters, M. L., & Evers, A. W. (2015). Inducing Expectations for Health: Effects of Verbal Suggestion and Imagery on Pain, Itch, and Fatigue as Indicators of Physical Sensitivity. PLOS ONE, 10(10), e0139563. https://doi.org/10.1371/journal.pone.0139563
  • Review: Van Laarhoven, A. I. M., Van der Sman-Mauriks, I., Donders, A. R. T., Pronk, M. C., Van de Kerkhof, P. C., & Evers, A. W. M. (2015). Placebo Effects on Itch: A Meta-Analysis of Clinical Trials of Patients with Dermatological Conditions. Journal of Investigative Dermatology, 135(5), 1234–1243. https://doi.org/10.1038/jid.2014.522
  • Bartels, D. J. P., Van Laarhoven, A. I. M., Haverkamp, E., Wilder-Smith, O. H., Donders, A. R. T., Van Middendorp, H., Van der Kerkhof, P. C. M., & Evers, A. W. M. (2014). Role of Conditioning and Verbal Suggestion in Placebo and Nocebo Effects on Itch. PLoS ONE, 9(3), e91727. https://doi.org/10.1371/journal.pone.0091727
  • Van Laarhoven, A. I. M., & Evers, A. W. M. (2011). Response to the commentary “You may (not always) experience what you expect: In search of the limits of the placebo and nocebo effect”. Pain, 152(8), 1931–1932. https://doi.org/10.1016/j.pain.2011.05.025
  • Van Laarhoven, A. I. M., Vogelaar, M. L., Wilder-Smith, O. H., Van Riel, P. L. C. M., Van de Kerkhof, P. C. M., Kraaimaat, F. W., & Evers, A. W. M. (2011). Induction of nocebo and placebo effects on itch and pain by verbal suggestions. Pain, 152(7), 1486–1494. https://doi.org/10.1016/j.pain.2011.01.043

* joint first authorship


Publications  on stress and emotions in chronological order


  • Van Loey, N. E. E., de Jong, A. E. E., Hofland, H. W. C. & van Laarhoven, A. I. M. (2022). Role of burn severity and posttraumatic stress symptoms in the co-occurrence of itch and neuropathic pain after burns: A longitudinal study. Frontiers in Medicine, 9, 997183. https://doi.org/10.3389/fmed.2022.997183
  • Evers, A. W. M., Verhoeven, E. W. M., Van Middendorp, H., Sweep, F. G. J., Kraaimaat, F. W., Donders, A. R. T., Eijsbouts, A. E., Van Laarhoven, A. I. M., De Brouwer, S. J. M., Wirken, L., Radstake, T. R. D. J., & Van Riel, P. L. C. M. (2013). Does stress affect the joints? Daily stressors, stress vulnerability, immune and HPA axis activity, and short-term disease and symptom fluctuations in rheumatoid arthritis. Annals of the Rheumatic Diseases, 73(9), 1683–1688. https://doi.org/10.1136/annrheumdis-2012-203143
  • Van Laarhoven, A. I. M., Walker, A. L., Wilder-Smith, O. H., Kroeze, S., Van Riel, P. L. C. M., Van de Kerkhof, P. C. M., Kraaimaat, F. W., & Evers, A. W. M. (2012). Role of induced negative and positive emotions in sensitivity to itch and pain in women. British Journal of Dermatology, 167(2), 262–269. https://doi.org/10.1111/j.1365-2133.2012.10933.x
  • Review: De Brouwer, S. J., Kraaimaat, F. W., Sweep, F. C., Creemers, M. C., Radstake, T. R., Van Laarhoven, A. I. M., Van Riel, P. L., & Evers, A. W. (2010). Experimental stress in inflammatory rheumatic diseases: a review of psychophysiological stress responses. Arthritis Research & Therapy, 12(3), R89. https://doi.org/10.1186/ar3016

* joint first authorship


Publications on psychophysics in chronological order


  • Review: Van Laarhoven, A. I. M., Marker, J. B., Elberling, J., Yosipovitch, G., Arendt-Nielsen, L., & Andersen, H. H. (2019). Itch sensitization? A systematic review of studies using quantitative sensory testing in patients with chronic itch. Pain, 160(12), 2661–2678. https://doi.org/10.1097/j.pain.0000000000001678
  • Review: Andersen, H. H., Akiyama, T., Nattkemper, L. A., Van Laarhoven, A. I. M., Elberling, J., Yosipovitch, G., & Arendt-Nielsen, L. (2018). Alloknesis and hyperknesis—mechanisms, assessment methodology, and clinical implications of itch sensitization. Pain, 159(7), 1185–1197. https://doi.org/10.1097/j.pain.0000000000001220
  • Andersen, H. H., Van Laarhoven, A. I. M., Justesen, F. D., Pedersen, J. B., Sørensen, L. L., Jensen, L. P., & Arendt-Nielsen, L. (2018). Capsaicin-sensitive cutaneous primary afferents convey electrically induced itch in humans. Neuroscience Letters, 666, 186–189. https://doi.org/10.1016/j.neulet.2017.11.061
  • Andersen, H. H.,* Van Laarhoven, A. I. M.,* Elberling, J., & Arendt-Nielsen, L. (2017). Modulation of Itch by Conditioning Itch and Pain Stimulation in Healthy Humans. The Journal of Pain, 18(12), 1437–1450. https://doi.org/10.1016/j.jpain.2017.07.002
  • Pereira, M. P., Pogatzki-Zahn, E., Snels, C., Vu, T. H., Üçeyler, N., Loser, K., Sommer, C., Evers, A. W. M., Van Laarhoven, A. I. M., Agelopoulos, K., & Ständer, S. (2017). There is no functional small-fibre neuropathy in prurigo nodularis despite neuroanatomical alterations. Experimental Dermatology, 26(10), 969–971. https://doi.org/10.1111/exd.13343
  • Van Laarhoven, A. I. M., Ulrich, D. J. O., Wilder-Smith, O. H., Loey, N. E. E., Nieuwenhuis, M., Van der Wee, N. J. A., & Evers, A. W. M. (2016). Psychophysiological Processing of Itch in Patients with Chronic Post-burn Itch: An Exploratory Study. Acta Dermato Venereologica, 96(5), 613–618. https://doi.org/10.2340/00015555-2323
  • Van Laarhoven, A. I. M., Kraaimaat, F. W., Wilder-Smith, O. H., Van Riel, P. L. C. M., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2013). Sensitivity to itch and pain in patients with psoriasis and rheumatoid arthritis. Experimental Dermatology, 22(8), 530–534. https://doi.org/10.1111/exd.12189
  • Van Laarhoven, A. I. M., Kraaimaat, F. W., Wilder-Smith, O. H., Van de Kerkhof, P. C. M., & Evers, A. W. M. (2010). Heterotopic pruritic conditioning and itch – Analogous to DNIC in pain? Pain, 149(2), 332–337. https://doi.org/10.1016/j.pain.2010.02.026
  • Van Laarhoven, A. I. M., Kraaimaat, F. W., Wilder-Smith, O. H., Van de Kerkhof, P. C. M., Cats, H., Van Riel, P. L. C. M., & Evers, A. W. M. (2007). Generalized and symptom-specific sensitization of chronic itch and pain. Journal of the European Academy of Dermatology and Venereology, 21(0), 1187–1192. https://doi.org/10.1111/j.1468-3083.2007.02215.x

* joint first authorship

Miscellaneous publications in chronological order


  • Review: Dominick, F.,* Van Laarhoven, A. I. M.,* Evers, A. W. M., & Weisshaar, E. (2019). A systematic review of questionnaires on itch by the Special Interest Group “Questionnaires” of the International Forum for the Study of Itch (IFSI). Itch, 4(3), e26. https://doi.org/10.1097/itx.0000000000000026
  • Review: Evers, A. W. M., Peerdeman, K. J., & Van Laarhoven, A. I. M. (2019). What is new in the psychology of chronic itch? Experimental Dermatology, 28(12), 1442–1447. https://doi.org/10.1111/exd.13992
  • Van Beugen, S., Maas, J., Van Laarhoven, A. I. M., Galesloot, T. E., Rinck, M., Becker, E. S., Van de Kerkhof, P. C. M., Van Middendorp, H., & Evers, A. W. M. (2016). Implicit stigmatization-related biases in individuals with skin conditions and their significant others. Health Psychology, 35(8), 861–865. https://doi.org/10.1037/hea0000404
  • Smits, T., Van Laarhoven, A. I. M., Staassen, A., Van de Kerkhof, P. C. M., Van Erp, P. E. J., & Gerritsen, M. J. (2009). Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells. British Journal of Dermatology, 160(4), 849–857. https://doi.org/10.1111/j.1365-2133.2008.09012.x

* joint first authorship

Publications on (psycho)neurophysiology in chronological order 


  • Millard, S. K., Bokelmann, K., Schalbroeck, R., Van der Wee, N. J. A., Van Loey, N. E. E., & Van Laarhoven, A. I. M. (2022). No indications for altered EEG oscillatory activity in patients with chronic post-burn itch compared to healthy controls. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-08742-8
  • Thomaidou, M. A.,* Blythe, J. S.,* Houtman, S. J.,* Veldhuijzen, D. S., Van Laarhoven, A. I. M., & Evers, A. W. M. (2021). Temporal structure of brain oscillations predicts learned nocebo responses to pain. Scientific Reports, 11, 9807. https://doi.org/10.1038/s41598-021-89368-0

* joint first authorship

Publications in national journals


  • Veldhuijzen, D. S., Van Laarhoven A. I. M. (2020).  De kracht van placebo en nocebo effecten: Toepassingen in de klinische praktijk. Nederlands Tijdschrift voor HandTherapie, 23-27.
  • Van Laarhoven, A. I. M. (2013). Inductie van nocebo- en placebo- effecten op jeuk en pijn door verbale suggestie. Nederlands Tijdschrift voor Dermatologie en Venereologie, 23, 14-15.
  • Van Laarhoven, A. I. M. (2012). Pijn en jeuk: Een vergelijking van psychofysiologische factoren. Nederlands tijdschrift voor pijn en pijnbestrijding, 51, 21-25.
  • Van Laarhoven, A. I. M. (2012). Jeuk en pijn: Psychofysiologische overeenkomsten en verschillen. Supplement, 6, 20-24.
  • Van Laarhoven, A. I. M. (2012). Psychofysiologie van jeuk en pijn: Two of a kind? Nederlands tijdschrift voor Dermatologie en Venereologie, 22, 449-451.
  • Van Laarhoven A. I. M. (2012). Jeuk en Pijn: Overeenkomstige en verschillende psychofysiologische factoren. Paradermica, 1, 12-17.
  • Evers, A. W. M., Duller, P., Verhoeven, E. W. M., Van Laarhoven, A. I. M., de Jong, E. M. G. J., van de Kerkhof, P. C. M. (2008). “Jeuk is erger dan pijn”. Gedragstherapie, 41, 5-14.

Book Chapters


  • Van Beugen, S., van Laarhoven, A. I. M., Spillekom-van Koulil, S., Evers, A. W. M. (2021). The psychology of itch: Current evidence and future directions. Book chapter for Comprehensive Clinical Psychology. 
  • Invited book chapter: Van Laarhoven, A. I. M., Peerdeman, K. J., van Ryckeghem, D. M., Evers, A. W. M. (2020). Cognitive processing of itch and pain: The role of attention and expectations. In: Yosipovitch, Andersen, Arendt-Nielsen, (Eds)., Itch and pain: Similarities, interactions and differences (pp. 289-298). Philadelphia, PA, Wolters Kluwer. 
  • Evers, A. W. M., Peerdeman, K. J., Bartels, D. J. P., van Laarhoven, A. I. M. (2016). Placebo and Nocebo Effects on Itch: Methodological and Clinical Implications. In Misery L., Ständer S. (Eds) Pruritus. Springer, 
  • Evers, A. W., Bartels, D. J., van Laarhoven, A. I. M. (2014). Placebo and nocebo effects in itch and pain. In Benedetti, F., Enck, P., Frisaldi, E., Schedlowski, M. (Eds.): Placebo. Handbook of Experimental Pharmacology. (pp. 205-214).

Contact
a.vanlaarhoven@fsw.leidenuniv.nl
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